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2008 Memphis Tigers basketball team: Ah, those pesky missed free throws. The Derrick Rose-led Tigers, who won an NCAA-record 38 games last season, blew a 9-point lead with 2:12 left in the Final Four championship game against Kansas. The Jayhawks won in overtime 75-68.
Phil Mickelson at the 2006 U.S. Open: Lefty took Winged Foot for a ride for 71 holes, looking poised to win his third consecutive major. Then his drive on 18 went left. And more left.
2002 Miami Hurricanes: Larry Coker's squad went 12-0 with a 24-point average margin of victory, only for Ohio State to outmuscle the Hurricanes in double overtime of the national championship game.
2001 Seattle Mariners : After tying a major-league Baseball record with 116 regular-season wins, Seattle's offense went frigid in a five-game ALCS loss to the New York Yankees .
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